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Lab
Efficiency

Implementing the American Society of Echocardiography (ASE) ultrasound enhancing agent guidelines into your facility's policy helps to ensure the appropriate use of DEFINITY® for improved patient care.1,2

Contrast Echo: See the Difference, Experience the Impact


Jonathan R. Lindner, MD, FACC, FASE, Lissa Sugeng, MD, MPH, FACC, FASE, and Rajesh Janardhanan, MD, MCRP, FACC, FASE, present the Lantheus 2015 ASE Science & Technology Theater Program.


DEFINITY® delivers clinical and economical value by improving diagnostic accuracy, lab efficiency, and workflow.3-5

Reduced resource utilization and per-patient expenses3

DEFINITY® helped 33% of patients avoid additional diagnostic procedures.

Eliminated the need for additional tests by 33%3

Associated with changes in use of vasoactive medications4

Reduced struggle time and may limit sonographer injury5,6,*

*Additional studies may be needed.

Decreased    
procedure time5

May increase  
patient throughput5,6

Peer-to-peer Programs

Lantheus offers multiple peer-to-peer programs to increase echo quality, enhance lab efficiency, reduce cost, and improve patient care.

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References:

  1. Porter TR, Mulvagh SL, Abdelmoneim SS, et al. Clinical applications of ultrasonic enhancing agents in echocardiography: 2018 American Society of Echocardiography guidelines update. J Am Soc Echocardiogr. 2018;31(3):241-274. doi:10.1016/j.echo.2017.11.013

  2. Mulvagh SL, Rakowski H, Vannan MA, et al. American Society of Echocardiography consensus statement on the clinical applications of ultrasonic contrast agents in echocardiography. J Am Soc Echocardiogr. 2008;21(11):1179-1281. doi:10.1016/j.echo.2008.09.009

  3. Kurt M, Shaikh KA, Peterson L, et al. Impact of contrast echocardiography on evaluation of ventricular function and clinical management in a large prospective cohort. J Am Coll Cardiol. 2009;53(9):802-810. doi:10.1016/j.jacc.2009.01.005

  4. Main ML, Fu JW, Gundrum J, LaPointe NA, Gillam LD, Mulvagh SL. Impact of contrast echocardiography on outcomes in critically ill patients. Am J Cardiol. 2021;150:117-122. doi:10.1016/j.amjcard.2021.03.039

  5. Lester SJ, Askew JW, Hurst RT, et al. Contrast echocardiography: experience in a clinical echocardiography laboratory. J Am Soc Echocardiogr. 2006;19(7);919-923. doi:10.1016/j.echo.2006.01.025

  6. Castello R, Bella JN, Rovner A, Swan J, Smith J, Shaw L. Efficacy and time-efficiency of a “sonographer-driven” contrast echocardiography protocol in a high-volume echocardiography laboratory. Am Heart J. 2003;145(3):535-541. doi:10.1067/mhj.2003.164

INDICATION

DEFINITY® is indicated, after activation, for use in adult and pediatric patients with suboptimal echocardiograms to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border.

IMPORTANT SAFETY INFORMATION

BOXED WARNING: SERIOUS CARDIOPULMONARY REACTIONS

Serious cardiopulmonary reactions, including fatalities, have occurred uncommonly during or following perflutren-containing microsphere administration. Most serious reactions occur within 30 minutes of administration.

  • Assess all patients for the presence of any condition that precludes DEFINITY® administration.
  • Always have resuscitation equipment and trained personnel readily available.

References:

  1. Porter TR, Mulvagh SL, Abdelmoneim SS, et al. Clinical applications of ultrasonic enhancing agents in echocardiography: 2018 American Society of Echocardiography guidelines update. J Am Soc Echocardiogr. 2018;31(3):241-274. doi:10.1016/j.echo.2017.11.013
  2. Mulvagh SL, Rakowski H, Vannan MA, et al. American Society of Echocardiography consensus statement on the clinical applications of ultrasonic contrast agents in echocardiography. J Am Soc Echocardiogr. 2008;21(11):1179-1281. doi:10.1016/j.echo.2008.09.009
  3. Kurt M, Shaikh KA, Peterson L, et al. Impact of contrast echocardiography on evaluation of ventricular function and clinical management in a large prospective cohort. J Am Coll Cardiol. 2009;53(9):802-810. doi:10.1016/j.jacc.2009.01.005 
  4. Main ML, Fu JW, Gundrum J, LaPointe NA, Gillam LD, Mulvagh SL. Impact of contrast echocardiography on outcomes in critically ill patients. Am J Cardiol. 2021;150:117-122. doi:10.1016/j.amjcard.2021.03.039 
  5. Lester SJ, Askew JW, Hurst RT, et al. Contrast echocardiography: experience in a clinical echocardiography laboratory. J Am Soc Echocardiogr. 2006;19(7);919-923. doi:10.1016/j.echo.2006.01.025 
  6. Castello R, Bella JN, Rovner A, Swan J, Smith J, Shaw L. Efficacy and time-efficiency of a “sonographer-driven” contrast echocardiography protocol in a high-volume echocardiography laboratory. Am Heart J. 2003;145(3):535-541. doi:10.1067/mhj.2003.164

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