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* MI settings for LVO will vary by contrast agent, patient and ultrasound system used.
* The safety of activated DEFINITY® at mechanical indices of >0.8 and with end-systolic triggering has not been established.5
- Burgess P, et al. Performing an echocardiographic examination with a contrast agent: a series on contrast echocardiography, article 2. J Am Soc Echocardiogr. 2000;13:629-636.
- Feigenbaum H. Feigenbaum's Echocardiography. 6th ed. Philadelphia, Pa. Lippencott Williams & Wilkins; 2005:11-45.
- Witt SA, et al. Achieving a diagnostic contrast-enhanced echocardiogram: a series on contrast echocardiography, article 4. J Am Soc Echocardiogr. 2001;14:327-334.
- McCulloch M, et al. Ultrasound contrast physics: a series on contrast echocardiography, article 3.
J Am Soc Echocardiogr. 200:13:959-967.
- DEFINITY® US Package Insert.
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Mechanical Index (MI)
- Measure of acoustic ultrasound power1
- High MI increases microsphere disruption1
- MI setting of <0.8 for LVO1*
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Focus
- Narrowest area of the ultrasound beam with the greatest ultrasound intensity2
- Place focal zone at the mitral valve level 1
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Receiver Gain
- Boosts the amplification of received echoes3
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Dynamic Range
- Adjusts the range of "shades of gray" displayed in the 2D image3
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Frame Rate
- Determines the number of frames per unit of time 2
- Affects microsphere disruption 4
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