Case Studies



Case Study Programs

Getting to the Bottom of the Problem
The Importance of Endocardial Border Delineation of the LV Myocardial Apex
Presented by:
Vincent Sorrell, MD
Natesa Pandian, MD

View Presentation


Interactive Case Studies

38 Year Old Woman Considered For Gastric Bypass Surgery
Images courtesy of M. Vannan, MBBS

38 Year Old Man With End Stage Renal Disease
Images courtesy of M. Vannan, MBBS

66 Year Old Woman With Increasing Heart Failure Symptoms
Images courtesy of M. Vannan, MBBS

47 Year Old Woman Presenting With Chest Pain
Images courtesy of Roberto Lang, MD, University of Chicago
Noninvasive Cardiac Imaging Laboratories


43 Year Old Man With Hypertension And HIV
Images courtesy of Regions Hospital, St. Paul MN

38 Year Old Woman With History of Myocardial Infarction
Images courtesy of Roberto Lang, MD, University of Chicago
Noninvasive Cardiac Imaging Laboratories


Case Study

Case Studies

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INDICATIONS

Activated DEFINITY® (Perflutren Lipid Microsphere) Injectable Suspension is indicated for use in patients with suboptimal echocardiograms to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border.

The safety and efficacy of DEFINITY® with exercise stress or pharmacologic stress testing have not been established.

CONTRAINDICATIONS

Do not administer DEFINITY® to patients with known or suspected right-to-left, bi-directional or transient right-to-left cardiac shunts, by intra-arterial injection, or to patients with known hypersensitivity to perflutren.

IMPORTANT SAFETY INFORMATION

WARNING: Serious Cardiopulmonary Reactions 

Serious cardiopulmonary reactions, including fatalities, have occurred during or following perflutren-containing microsphere administration.

  • Assess all patients for the presence of any condition that precludes DEFINITY® administration (see CONTRAINDICATIONS).
  • In patients with pulmonary hypertension or unstable cardiopulmonary conditions, monitor vital sign measurements, electrocardiography and cutaneous oxygen saturation during and for at least 30 minutes after DEFINITY® administration (see WARNINGS).
  • Always have resuscitation equipment and trained personnel readily available.


In post marketing use, rare but serious cardiopulmonary or anaphylactoid reactions have been reported during or shortly following perflutren-containing microsphere administration (see ADVERSE REACTIONS). The risk for these reactions may be increased among patients with pulmonary hypertension or unstable cardiopulmonary conditions. It is not always possible to reliably establish a causal relationship to drug exposure due to the presence of underlying cardiopulmonary disease.

Please See Full Prescribing Information and Letter to Healthcare Providers.

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